Coronavirus Disease 2019 (COVID-19) was declared as pandemic by the World Health Organization on March 11th, 2020. It is no secret the world has suffered through other deadly pandemics, but with the recent spread of Covid-19 a new study adds evidence for Cannabis as a potential way to prevent Covid-19.
As we continue to see a rise in cases of the coronavirus, the world continues to wait and hope for a sure solution to be discovered that might treat, cure or prevent this unknown deadly disease. What may seem surprising, is cannabis is on the list of potential treatments.
In a recent article posted by Forbes.com we are told that researchers are exploring many different possibilities in combating COVID-19, some researchers are looking into whether cannabis or cannabis derived CBD might offer benefits for those suffering from severe forms of this infection. Interestingly, there have been several different ways researchers have suggested CBD might help, including its ability to reduce ACE2 expression and pro-inflammatory cytokine production to fight lung inflammation, and it’s potential as an antiviral. But few studies have tested these theories with actual experimentation.
Now new evidence is adding support to the theory that cannabis derived CBD may help those suffering from the severe lung inflammation that occurs in more serious cases of COVID-19. The study from researchers at Augusta University in Georgia suggests that CBD may positively impact ARDS or acute respiratory distress syndrome - a dangerous symptom in COVID-19 caused by an overactive inflammatory response. This is sometimes referred to as a ‘cytokine storm’. The authors of the study explain that “currently, other than supportive measures, there is no definitive cure for ARDS, illustrating the urgent need for creative and effective therapeutic modalities to treat this complex condition.”
But CBD may be able to help treat this dangerous symptom of COVID-19. The researchers suggest CBD may be able to help by reducing pro-inflammatory cytokine production, fighting off the storm. By reducing specific cytokines such as interleukin (IL)-6, IL-1b, and IL-17, we may be able to bring down the inflammation and thus end the respiratory distress and damage. And the results of these researchers' experiments supported this theory.
Two Canadian researchers think that a special strain of cannabis might potentially be a valuable tool in the fight against COVID-19.
The researchers, Olga and Igor Kovalchuck have reportedly been developing and testing a novel cannabis strain for years, except with the goal of creating a strain that helps to combat cancer and inflammation. When the pandemic hit, the duo started to focus their efforts on how the strain might be used to help fight COVID-19.
The duo’s work was published in an April issue of the online medical journal Preprints.
“Similar to other respiratory pathogens, SARS-CoV2 is transmitted through respiratory droplets, with potential for aerosol and contact spread. It uses receptor-mediated entry into the human host via angiotensin-converting enzyme II (ACE2) that is expressed in lung tissue, as well as oral and nasal mucosa, kidney, testes, and the gastrointestinal tract,” reads the study. “Modulation of ACE2 levels in these gateway tissues may prove a plausible strategy for decreasing disease susceptibility.”
A Canadian study finds that enzymes in cannabis could treat COVID-19
Researchers at the University of Lethbridge recently released results from a study that shows the benefits of CBD as an aid in blocking the cells that enter the body from the novel coronavirus.
The study, published in peer journal Preprints, was conducted by the scientists in April, and the results were released in a non-peer-reviewed, preclinical study titled "In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues" earlier this month, according to a release from pharmaceutical research company Pathway RX.